The purpose of tetracycline hydrochloride conditioning of root surfaces in periodontal surgery is to:

The purpose of tetracycline hydrochloride conditioning of root surfaces in periodontal surgery is primarily to enhance the binding of fibronectin and fibroblasts to the treated surfaces. Tetracycline is an antibiotic that not only has antibacterial properties but also plays a significant role in altering the surface characteristics of the root. When root surfaces are conditioned with tetracycline, it promotes the adsorption of proteins such as fibronectin, which is crucial for cell adhesion and subsequent healing processes. By facilitating the binding of fibroblasts, which are essential for tissue regeneration, tetracycline conditioning supports periodontal healing and improves the overall outcomes of the surgical procedure.

This conditioning process does not sterilize the root surface; while it may help reduce pathogen load, its primary action is not to eliminate all bacteria. Also, it does not directly remineralize the root surface; remineralization generally involves processes that restore the mineral content of the tooth structure, which is not the focus of tetracycline usage in this context. Lastly, while the use of tetracycline can potentially reduce the risk of infection through its antibacterial effects, its main indication in periodontal surgery is to enhance cellular activity and promote healing rather than solely serving as a preventative measure against infections.